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KMID : 0352119890050020128
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Journal of Kyung Hee University
1989 Volume.5 No. 2 p.128 ~ p.132
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CARDIOVASCULAR RESPONSE BY INTRAVENOUS LIDOCAINE INJECTION IN ENDOTRACHEAL EXTUBATION
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Abstract
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Increases in blood pressure and heart rate at the end of anesthesia and just after endotracheal extubation are common and may produce dangerous state in the patients with hypertension and coronary or cerbral vascular insufficiency.
The purpose of this study is to investigate the effects of blood pressure and heart rate responses to endotracheal extubation with and without prior intravenous administration of 2% lidocaine (1 mg,/kg).
Fourty patients who received elective operation under general anesthesia were selected and divided into two groups, such as followings:
Group I: receiving 2% lidocaine injection (1 mg/kg) before endotracheal extubation
Group II:receiving 3 ml saline injection before endotracheal extubation
And arterial blood pressure, heart rate, coughing reflex were checked two minutes before extubation,
during extubation, one minute after extubation and 68 mint tes after extubation.
Tl a results were as followings:
1) Arterial blood pressure and heart rate during and after extubation in group I were increased compared with those of two minutes before extubation, but there was statistically no significancy (p>0.05).
2) Arterial blood pressure and heart rate during and after extubation in group II were significantly increased comb: ared with those of two minutes before extubation (p<(1.005).
3) ~oughing reflex after extubation was occured in the nine patients among group II (twenty patients).
Th ~ above findings suggest that the intravenous injection A lidocaine before extubation may alleviate the cardi )vascular responses and coughing reflex to extubation.
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